Autonomous Magnetic Microrobots by Navigating Gates for Multiple Biomolecules Delivery

The precise delivery of biofunctionalized matters is of great interest from the fundamental and applied viewpoints. In spite of significant progress achieved during the last decade, a parallel and automated isolation and manipulation of rare analyte, and their simultaneous on‐chip separation and trapping, still remain challenging. Here, a universal micromagnet junction for self‐navigating gates of microrobotic particles to deliver the biomolecules to specific sites using a remote magnetic field is described. In the proposed concept, the nonmagnetic gap between the lithographically defined donor and acceptor micromagnets creates a crucial energy barrier to restrict particle gating. It is shown that by carefully designing the geometry of the junctions, it becomes possible to deliver multiple protein‐functionalized carriers in high resolution, as well as MCF‐7 and THP‐1 cells from the mixture, with high fidelity and trap them in individual apartments. Integration of such junctions with magnetophoretic circuitry elements could lead to novel platforms without retrieving for the synchronous digital manipulation of particles/biomolecules in microfluidic multiplex arrays for next‐generation biochips.     

Monitoring agricultural drought for arid and humid regions using multi-sensor remote sensing data

While existing remote sensing-based drought indices have characterized drought conditions in arid regions successfully, their use in humid regions is limited. We propose a new remote sensing-based drought index, the Scaled Drought Condition Index (SDCI), for agricultural drought monitoring in both arid and humid regions using multi-sensor data. This index combines the land surface temperature (LST) data and the Normalized Difference Vegetation Index (NDVI) data from Moderate Resolution Imaging Spectroradiometer (MODIS) sensor, and precipitation data from Tropical Rainfall Measuring Mission (TRMM) satellite. Each variable was scaled from 0 to 1 to discriminate the effect of drought from normal conditions, and then combined with the selected weights. When tested against in-situ Palmer Drought Severity Index (PDSI), Palmer's Z-Index (Z-Index), 3-month Standardized Precipitation Index (SPI), and 6-month SPI data during a ten-year (2000-2009) period, SDCI performed better than existing indices such as NDVI and Vegetation Health Index (VHI) in the arid region of Arizona and New Mexico as well as in the humid region of North Carolina and South Carolina. The year-to-year changes and spatial distributions of SDCI over both arid and humid regions generally agreed to the changes documented by the United States Drought Monitor (USDM) maps.     

Design of a sliding mode controller for an automatic guided vehicle and its implementation

In this paper, a control scheme that combines a kinematic controller and a sliding mode dynamic controller with external disturbances is proposed for an automatic guided vehicle to track a desired trajectory with a specified constant velocity. It provides a method of taking into account specific mobile robot dynamics to convert desired velocity control inputs into torques for the actual mobile robot. First, velocity control inputs are designed for the kinematic controller to make the tracking error vector asymptotically stable. Then, a sliding mode dynamic controller is designed such that the mobile robot’s velocities converge to the velocity control inputs. The control law is obtained based on the backstepping technique. System stability is proved using the Lyapunov stability theory. In addition, a scheme for measuring the errors using a USB camera is described. The simulation and experimental results are presented to illustrate the effectiveness of the proposed controller.     

Studies on a LaF3‐coated MgO protecting layer in AC‐plasma‐display panels

A new protecting layer, a LaF₃‐coated MgO layer, in color AC‐plasma‐display panels (PDPs) was studied in order to overcome the weakness of the conventional single MgO protecting layer. The material characteristics of the new layer were examined by using variations in the deposition process. The display characteristics were also examined by implementing their processes to actual PDPs. It was demonstrated that this method is effective in lowering the firing and sustaining voltages of PDPs and enhancing the brightness of the panel as well.     

Adaptive crossover,mutation and selection using fuzzy system for genetic algorithms

Genetic algorithms use a tournament selection or a roulette selection to choice better population. But these selections couldn’t use heuristic information for specific problem. Fuzzy selection system by heuristic rule base help to find optimal solution efficiently. And adaptive crossover and mutation probabilistic rate is faster than using fixed value. In this paper, we want fuzzy selection system for genetic algorithms and adaptive crossover and mutation rate fuzzy system. This work was presented in part and awarded as Young Author Award at the 13th International Symposium on Artificial Life and Robotics, Oita, Japan, January 31–February 2, 2008     

Proteinase activity in the isolates of Trichomonas vaginalis according to their pathogenicity

Ten axenic isolates of Trichomonas vaginalis were subcutaneously injected to the BALB/c mice in order to assess their pathogenicity by means of so-called "mouse assay" method. All the isolates revealed neutral and acid proteinase activities both in their lysates and in culture media, but the specific activities of both proteinases in the severely pathogenic group were significantly higher than the mildly pathogenic group (p < 0.05). In the SDS-PAGE system in which the electrophoretic gels contained 0.4% gelatin as the substrate, five different banding patterns of trichomonal proteinases were detected, and the patterns were closely related with the pathogenicity of the isolates of T. vaginalis. All five bands might be regarded as cysteine proteinases group in the inhibitor assays. The cytotoxicity of the lysates of T. vaginalis to the target Chinese hamster ovarian (CHO) cell line was also significantly different according to the pathogenicity of the isolates, and generally lower in the lysates treated with cysteine proteinase inhibitors than in the control lysates. In summarizing the results, it might be considered that the proteinases of T. vaginalis showing five electrophoretic banding patterns are closely related with the pathogenicity and cytotoxicity of the isolates of T. vaginalis.     

MLS‐based variable‐node elements compatible with quadratic interpolation. Part I: formulation and application for non‐matching meshes

Two‐dimensional variable‐node elements compatible with quadratic interpolation are developed using the moving least‐square (MLS) approximation. The mapping from the parental domain to the physical element domain is implicitly obtained from MLS approximation, with the shape functions and their derivatives calculated and saved only at the numerical integration points. It is shown that the present MLS‐based variable‐node elements meet the patch test if a sufficiently large number of integration points are employed for numerical integration. The cantilever problem with non‐matching meshes is chosen to check the feasibility of the present MLS‐based variable‐node elements, and the result is compared with that from the lower‐order case compatible with linear interpolation. Copyright © 2005 John Wiley & Sons, Ltd.     

Development of the PenTile Matrix™ color AMLCD subpixel architecture and rendering algorithms

Abstract— Color subpixel rendering is enhanced by co‐optimizing the color subpixel architecture and algorithms with respect to human vision. This has resulted in the PenTile? display technology, which provides double the information content per subpixel when compared to a conventional RGB Stripe display. Output performance results from mathematical modeling, software simulations, and prototype AMLCDs displays demonstrate significant quality improvements to both text and full‐color images in comparison to images from RGB Stripe displays that have the same number of subpixels and column drivers.     

The effect of temperature and extrusion speed on the consolidation of zirconium-based metallic glass powder using equal-channel angular extrusion

In this study, gas-atomized amorphous Zr_58.5Nb_2.8Cu_15.6Ni_12.8Al_10.3 (Vitreloy 106a) containing 1280 ppmw oxygen was consolidated by equal-channel angular extrusion (ECAE). The powder was vacuum encapsulated in copper cans and subjected to one extrusion pass in the temperature region above the glass transition temperature (T _g) and below the crystallization temperature (T _x). The effects of extrusion temperature and the extrusion rate on microstructure, thermal stability, hardness, and compressive strength are investigated. Compression fracture surfaces were examined to determine the deformation mechanisms. The consolidates in which the time-temperature-transformation (TTT) boundary was not crossed during processing exhibit differential scanning calorimetry (DSC) patterns similar to the initial powder, with a slight decrease in T _x. Compressive strengths of about 1.6 GPa are recorded in the consolidates processed at 30 °C and 40 °C below T _x, which is close to what is observed in cast counterparts. The fracture surfaces exhibit vein patterns covering up to 90 pct of the surface area in some samples, which are characteristic of glassy material fracture. The slight decrease in T _x after consolidation is attributed to thermal-history-dependent short-range order and formation of nanocrystalline islands. The present results show that ECAE is successful in consolidation of metallic glass powder. This processing avenue opens a new opportunity to fabricate bulk metallic glasses (BMGs) with dimensions that may be impossible to achieve by casting methods.     

Science and Technology of High Dielectric Constant Thin Films and Materials Integration for Application to High Frequency Devices

Thin films of Ba_1?x Sr _x Ti_1+y O_3+z (BST), were fabricated using both by RF-magnetron sputtering and MOCVD to demonstrate application to high frequency devices. Precise control of composition and microstructure is critical for the production of (Ba _x Sr_1?x )Ti_1+y O_3+z (BST) dielectric thin films with the large dependence of permittivity on electric field, low losses, and high electrical breakdown fields that are required for successful integration of BST into tunable high frequency devices. Here we review results on composition-microstructure-electrical property relationships of polycrystalline BST films produced by magnetron sputter deposition that are appropriate for microwave devices such as phase shifters. BST films with a multilayer structure were also developed with different Ti-elemental ratio in each layer to minimize losses and leakage current. Interfacial contamination from C and H species was studied and implications on electrical properties are highlighted. Finally, York's group at the University of California-Santa Barbara successfully integrated our BST films onto phase shifter arrays. The results show potential of BST films in such applications. Results from initial work on the integration of Cu-electrodes with BST films are also presented.